Episode 1001 of Holby City is broadcast in England/Wales/Northern Ireland, Tuesday 12 November 2019, on BBC One at 20:00.
Viewers in Scotland will have the same episode, Tuesday 12 November 2019, on BBC One at 22:45.
Devised by Paul Unwin / Jeremy Brock
Devised by Tony McHale / Mal Young
Written by Damian Mullen
Directed by Thomas Hescott
Series Producer: Jane Wallbank
Series Producer: Yasmin Kalli
Executive Producer: Simon Harper
A paranoid Jac feels she is the centre of hospital gossip when word spreads Emma is now living with Jonny.
As Elliot’s concern for Jac grows, will he ever be able to tell her his secret?
Lofty is determined to be there for his new family, but will it be smooth sailing from here?
Lofty resolves to put his new family first, but even the basics of parenting stir up trouble between him, Helen and Dom.
Sacha struggles with his feelings for Essie, which seem doomed to go unrequited.
Rosie Marcel as Jac Naylor
Amy Lennox as Chloe Godard
Jo Martin as Max McGerry
David Ames as Dominic "Dom" Copeland
Kaye Wragg as Essie Di Lucca
Lee Mead as Ben "Lofty" Chiltern
Belina Owusu as Nicky McKendrick
Alex Walkinshaw as Adrian "Fletch" Fletcher
Catherine Russell as Serena Campbell
Jaye Jacobs as Donna Jackson
Dawn Steele as Ange Godard
Marcus Griffiths as Xavier "Zav" Duval
Ramin Karimloo as Kian Madani
Bob Barrett as Sacha Levy
Paul Bradley as Eilliot Hope
Jules Robertson as Jason Haynes
Verity Marshall as Helen Pidge
Tanya Burr as Joanne Pearsons
Vicky Entwistle as Sandra Jackson